ABSTRACT
Objective:To investigate the clinical characteristics and prognostic factors of 2019 novel coronavirus (2019-nCoV) Omicron variant infected cases.Methods:A total of 987 coronavirus disease 2019 (COVID-19) adult imported cases admitted to Shanghai Public Health Clinical Center, Fudan University from July 1, 2021 to January 6, 2022 were recruited. The cases were divided into Omicron group (193 cases) and non-Omicron group (794 cases) according to the genotype of the virus. The clinical data, imaging examination and laboratory results of two groups were collected and compared. Chi-square test and Mann-Whitney U test were used as statistical methods. Multiple linear regression analysis was used for multiple linear regression analysis. Results:The majority of patients in Omicron group were 18 to 30 years old, accounting for 51.3%(99/193), which was higher than 31.4%(249/794) in non-Omicron group. The difference was statistically significant ( χ2=52.75, P<0.001). The proportion of mild cases in Omicron group was 88.6%(171/193), which was higher than 81.6%(648/794) in non-Omicron group. The difference was statistically significant ( χ2=5.37, P=0.021). Cases with symptoms were more common in Omicron group than those in non-Omicron group (60.1%(116/193) vs 29.1%(231/794)), and the difference was statistically significant ( χ2=65.49, P<0.001), with the main clinical manifestations of sore/itchy throat, fever and cough/expectoration. The proportion of cases with pulmonary computed tomography (CT) imaging manifestations at admission in Omicron group was 13.0%(25/193), which was lower than that in non-Omicron group (215/794, 27.1%). The difference was statistically significant ( χ2=16.83, P<0.001). The proportion of cases with 2019-nCoV IgG positive at admission was 47.7%(92/193) in Omicron group, which was lower than 61.1%(485/794) in non-Omicron group, and the difference was statistically significant ( χ2=11.51, P<0.001). The hospitalization time of Omicron group was 20.0 (16.0, 23.0) d, which was longer than that of non-Omicron group (14.0 (10.0, 22.0) d), and the difference was statistically significant ( Z=-7.42, P<0.001). Multiple linear regression analysis showed that the time of hospitalization of cases with 2019-nCoV IgG positive at admission was shorter, while that of the cases with fever in Omicron group was longer (both P<0.050). Conclusions:The main clinical characteristics of cases with Omicron variant are fever and upper respiratory symptoms. Their pulmonary CT imaging manifestations are less, and the time of hospitalization is slightly longer. The time of hospitalization and the virus clearance time in Omicron variant infected cases with 2019-nCoV IgG positive at admission and not presented with fever are both shorter.
ABSTRACT
INTRODUÇÃO: A prematuridade no Brasil corresponde a 12,4% dos nascidos vivos e é definida como o nascimento inferior a 37 semanas de gestação. Por conta da imaturidade de órgãos e sistemas, o recém-nascido pode apresentar diversas complicações e consequentemente maior tempo de internação nas unidades hospitalares, levando à uma maior morbidade e mortalidade nesta população. O período de internação dificulta o estabelecimento do vínculo entre os recém-nascidos e os seus pais. Por isso, técnicas como o método canguru que visam fortalecer esse vínculo são cada vez mais estudadas e aplicadas nestas unidades. O objetivo do presente trabalho é avaliar através de uma revisão de literatura se o método canguru influencia no tempo de internação do recém-nascido prematuro em unidades hospitalares. MÉTODO: Trata-se de um estudo de revisão integrativa de literatura com busca de artigos nas bases de dados eletrônicas Portal Regional da Biblioteca Virtual em Saúde (BVS), PubMed, Cochrane, Physiotherapy Evidence Database (PEDro) e EBSCO host com a utilização do cruzamento de quatro descritores em inglês e português indexados respectivamente no Medical Subject Headings (MeSH) e Descritores em Ciências da Saúde (DeCS). Foram inclusos estudos publicados no período 2008 a 2020. RESULTADOS: Foram incluídos 22 artigos com um total de 7.564 pacientes e sete parâmetros relacionados à alta hospitalar. Os resultados evidenciaram melhora nos sinais vitais, quadro álgico, sono, taxas de crescimento, regulação hormonal e facilitação neurocomportamental. CONCLUSÃO: Os achados indicaram que o método canguru influencia na melhora do quadro clínico do recém-nascido prematuro, contribuindo para uma melhor estabilização do quadro e consequente redução no período de internamento.
INTRODUCTION: Prematurity in Brazil corresponds to 12.4% of live births and is defined as birth less than 37 weeks of gestation. Due to the immaturity of organs and systems, the newborn can present several complications and, consequently, a longer stay in hospital units, leading to greater morbidity and mortality in this population. The hospitalization period makes it difficult to establish a bond between newborns and their parents. For this reason, techniques such as the kangaroo method that aims to strengthen this bond are increasingly studied and applied in these units. The present study aims to assess, through a literature review, whether the kangaroo method influences the length of hospital stay of premature newborns in hospital units. METHOD: This is an integrative literature review study with the search for articles in the electronic databases Regional Portal of the Virtual Health Library(VHL), PubMed, Cochrane, Physiotherapy Evidence Database (PEDro), and EBSCO host with the crossing of four descriptors in English and Portuguese indexed respectively in the Medical Subject Headings (MeSH) and Health Sciences Descriptors (DeCS). Studies published from 2008 to 2020 were included. RESULTS: 22 articleswere included with a total of 7.564patients and seven parameters related to hospital discharge. The results showed an improvement in vital signs, pain, sleep, growth rates, hormonal regulation, and neurobehavioral facilitation. CONCLUSION: The findings indicated that the kangaroo method influences the improvement of the clinical condition of the premature newborn, contributing to better stabilization of the condition and consequent reduction in the period of hospitalization.
Subject(s)
Kangaroo-Mother Care Method , Infant, Premature , HospitalizationABSTRACT
As informações no leito, sobre a necessidade de manobras do paciente, em intervalos de 2 h, para evitar o aparecimento de lesões por pressão podem reduzir o tempo de permanência, diminuir o risco de lesões de pele e os custos de manutenção do paciente.
Bedside information on the need for repositioning the patient at 2 h intervals to avoid the appearance of pressure ulcers can reduce hospitalization time, risk of skin lesions, and maintenance costs.